| |
|
| Research Interests: |
| |
| Mathematical modeling in the context of Systems Biology and Systems Medicine |
| - | Multi-Scale Modelling of Mechano-Electrophysiology of the Heart |
| - | Dynamic Protein Machinery of Sarcomeric Contraction |
| Advanced analytics of quantitative data |
| - | Development of a Data Analysis Methods for Mass Spectrometry |
|
| Publications: |
|
|
|
| Sophia Ohnemus, Linda Tillert, Roberta De Zio, Raluca-Andreea Tifrea, Andries Napo Leemisa, Simon Beyer, Peter Kohl, V. Timmermann, Franziska Schneider-Warme^, Johannes Vierock^:
Experimentally Informed, Quantitative Photocycle Model of the Light-Gated Potassium Channel WiChR
Biophysical Journal, 2026, 117(12): 2471-2485.
|
|
| Sophia Ohnemus, Kristing Fullerton, Leto L. Riebel, Mary M. Maleckar, Andrew D. McCulloch, V. Timmermann^, Gabriel Balaban^:
Low Complexity Elasticity Models for Cardiac Digital Twins
arXiv, 2025.
|
|
| Julian Freytag*, Simon Beyer, Jens Timmer, V. Timmermann^:
A Likelihood-Based Framework for Analysing Sarcomeric Protein Machinery in Cardiac Myocyte Models
Computing in Cardiology, 2025, CinC:1-4.
|
|
| V. Timmermann*, S. T. Wall, J. Sundnes, T. Lawen, P. A. Baumeister, T. A. Quinn, A. D. McCulloch, A. G. Edwards:
An In-Silico Study on Integrated Mechanisms of Mechano-Electric Feedback in Ischemic Arrhythmia
arXiv, 2023
|
|
| G. Tumlinson*, E. Chleilat, J. Madl, P. Kohl, V. Timmermann:
Quaternion-Aligned Electroanatomical Models of the Murine Atria from Standard-Output Functional and Structural Imaging
arXiv, 2023.
|
|
| R. Emig*, C. M. Zgierski-Johnston, V. Timmermann, A. J. Tabener, M. P. Nash, P. Kohl, R. Peyronnet:
Passive Myocardial Mechanical Properties: Meaning, Measurement, Models
Biophysical Reviews, 2021, 13(5):587-610.
|
|
| V. Timmermann*, A. D. McCulloch:
Mechano-Electric Coupling and Arrhythmogenic Current Generation in a Computational Model of Coupled Myocytes
Frontiers in Physiology, 2020, 11:519951.
|
|
| V. Timmermann*, A. G. Edwards, S. T. Wall, J. Sundnes, A. D. McCulloch :
Arrhythmogenic Current Generation by Myofilament-Triggered Ca2+ Release and Sarcomere Heterogeneity
Biophysical Journal, 2019, 117(12):2471-2485.
|
|
| V. Timmermann*, L. A. Dejgaard, K. H. Haugaa, A. G. Edwards, J. Sundnes, A. D. McCulloch, S. T. Wall:
An Integrative Appraisal of Mechano-Electric Feedback Mechanisms in the Heart
Progress in Biophysics and Molecular Biology, 2017, 130(Pt B): 404-417.
|
|
|
* first author, ^ last author
|
|
|
| Curriculum Vitae: |
| |
| since 02/2026 | Independent Group Leader 'Cardiac Systems Biology'
Institute of Physics (Prof. J. Timmer) and
Institute of Molecular Medicine (Prof. C. Borner), Freiburg (GER) |
| 02/2024-01/2026 | Junior Group Leader and Hans A. Krebs Digital Medical Scientist
Institute of Physics (Prof. J. Timmer) and
Institute of Molecular Medicine (Prof. C. Borner), Freiburg (GER) |
| 01/2021 - 12/2023 | Head of IT
Institute for Experimental Cardiovascular Medicine, Freiburg (GER) |
| 07/2019 - 12/2020 | Postdoctoral Researcher
Institute of Engineering in Medicine (Prof. A. D. McCulloch), University of California San Diego (USA) |
| 01/2017 - 12/2019 | Visiting Researcher (Multiple Short-Term Visits)
Institute of Engineering in Medicine (Prof. A. D. McCulloch), University of California San Diego (USA) |
| 10/2016 | Visiting Researcher
School of Biomedical Imaging Sciences (Prof. S. Niederer), King's College London, (UK) |
| 01/2016 - 09/2016 | Visiting Researcher
Institute of Engineering in Medicine (Prof. A. D. McCulloch), University of California San Diego, (USA) |
| 01/2015 | Visiting Researcher
Computational Biology Group (Dr. J. J. Rice), IBM T. J. Watson Research Center, Yorktown Heights (USA) |
| 09/2013 - 10/2014 | Student Research Assistant
Fraunhofer-Institute for Technical and Economic Mathematics, Kaiserslautern (GER) |
| 08/2012 - 10/2014 | M. Sc. in Mathematics International
Technical University of Kaiserslautern (GER) and National University of Singapore (SGP) |
| 10/2008 - 09/2012 | B. Sc. in Mathematics
Technical University of Kaiserslautern (GER) and Nantes Universite (FRA) |
| 06/2008 | Abitur at Gymnasium Kaltenkirchen, Kaltenkirchen (GER) |
| 11/1989 | Born in Hamburg (GER) |
| |
