Dr. Franz-Georg Wieland
Institute of Physics
University of Freiburg
Hermann-Herder Str. 3
79104 Freiburg
Email: franz-georg.wieland -at- fdm.uni-freiburg.de
Links
Research Interests
My research lies at the intersection of systems biology, biotechnology, and data science. I am particularly fascinated by how complex biological processes can be understood, modeled, and influenced through computational and experimental approaches.
- Understanding cellular decision-making through mathematical modeling
- Investigating phase separation and its role in autophagy and gene regulation
- Designing light-controlled systems for precise gene expression (optogenetics)
- Developing and applying advanced methods for parameter estimation and uncertainty quantification
- Creating interoperable tools and standards for systems biology modeling
- Exploring safety switches in therapeutic cellular engineering
- Applying artificial intelligence and wearable sensor data in sports science and healthcare
- Enhancing match analysis through predictive modeling and performance metrics
Publications
- Link to ORCID
- Doctoral thesis: Modelling complex and dynamical phenomena of systems biology, systems medicine, and sports science (link)
- Master thesis: Bayesian parameter estimation in systems biology: Markov chain Monte Carlo sampling of biochemical networks (link)
- Bachelor thesis: Implementation and assessment of optimization approaches for parameter estimation in systems biology (link)